A randomized controlled trial of Vonoprazan for the healing of artificial ulcers after endoscopic submucosal dissectio
- Conditions
- gastric tumor
- Registration Number
- JPRN-UMIN000022377
- Lead Sponsor
- Department of Gastroenterology and Hepatology Hokkaido University Graduate School of Medicine
- Brief Summary
A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 146
Not provided
1)Patient who cannot discontinue medicine such as PPI, H2blocker and gastroprotective for 1 week before ESD 2)Patients with history of surgery that affects gastric-acid secretion 3)Patients with Zollinger-Ellison syndrome 4)Patients cannot start oral administration 5) Patients with a history of allergy to the investigational product 6)Patients with a serious complication of liver failure 7)Patients with a serious complication of renal failure 8)Patients who cannot make their decision 9)Patients in pregnancy or may be pregnant 10)Patients during breastfeeding 11)Patients treated with atazanavir sulfate (Reyataz) or rilpivirine hydrochloride (Edurant) 12)Patient taking medicine such as theophylline, tacrolimus hydrate, digoxin, methyldigoxin, itraconazole, Gefitinib, methotrexate, phenytoin, Diazepam
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ratio of post-ESD scar after 4 weeks of gastric ESD
- Secondary Outcome Measures
Name Time Method redaction ratio of post-ESD ulcer after 4 weeks of gastric ESD