The effect of the combination of vitex agnus castus`s phytoestrogen and magnesium on fracture healing.
Not Applicable
Completed
- Conditions
- Condition 1: Fracture of shaft of femur. Condition 2: Fracture of shaft of tibia. Condition 3: Fracture of shaft of humerus. Condition 4: Fracture of shafts of both ulna and radius.Fracture of shaft of femurFracture of shaft of tibiaFracture of shaft of humerusFracture of shafts of both ulna and radius
- Registration Number
- IRCT2012092810955N1
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 64
Inclusion Criteria
Women with fracture in long bone (femur, tibia, humerus, radius or ulna); 20-45-year-old. Exclusion criteria: Pregnant or lactating; postmenopausal women; medications for any chronic disease (cancer, diabetes, CVD); use of medication known to affect bone metabolism; use of herbal drug contain phytoestrogen, use of supplements ( multivitamin-minerals,...), diuretics, hormonal drugs; Smoking; Alcohol consumption.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum Alkaline phosphatase. Timepoint: Before and 2 months after intervention. Method of measurement: Calorimetry method.;Serum Osteocalcin. Timepoint: Before and 2 months after intervention. Method of measurement: ELISA kit.;Serum Vaso Endothelial Growth Factor. Timepoint: Before and 2 months after intervention. Method of measurement: ELISA kit.;Callus formation. Timepoint: Before and 2 months after intervention. Method of measurement: Radiographic Evidence.
- Secondary Outcome Measures
Name Time Method