Probiotics' Effects on Hormones, Body and Mood in Obese Women
Not Applicable
Recruiting
- Conditions
- Obesity, Women
- Registration Number
- NCT07013409
- Lead Sponsor
- Wecare Probiotics Co., Ltd.
- Brief Summary
To evaluate the regulatory effect of probiotics formula on visceral fat metabolism and sex hormone balance in obese women.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
- Age: 18 to 40 years old, female, BMI ≥ 25 kg/m2.
- Be willing to receive follow-up during the intervention period.
- Be willing to provide two blood, urine and fecal samples during the intervention period.
- Be willing to take the compound probiotics by oneself every day during the intervention period.
- Have good hearing and be able to hear and understand all instructions during the intervention period.
Exclusion Criteria
- Suffering from digestive system diseases, mainly gastrointestinal diseases (celiac disease, ulcerative colitis, Crohn's disease).
- Suffering from severe neurological disorders (epilepsy, stroke, severe head trauma, meningitis within the past 10 years, brain surgery, brain tumor, long-term coma - excluding general anesthesia).
- Have received/are currently receiving treatment for the following mental illnesses: alcohol/drug/substance abuse dependence, schizophrenia, psychosis, bipolar disorder.
- Take medication for depression or low mood.
- Suffering from internal organ failure (such as heart, liver or kidney failure, etc.).
- Have received radiotherapy or chemotherapy in the past.
- Have received general anesthesia surgery/procedures within the past three years, or plan to receive general anesthesia procedures/surgeries within the next three months during this trial.
- Have suffered from hepatitis (hepatitis B, hepatitis C), HIV or syphilis in the past.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method The changes of estradiol before and after the intervention 0, 1, 2, 3 months The serum estrogen content of the subjects before and after the intervention was detected by enzyme-linked immunosorbent assay.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
The First Affiliated Hospital of Zhengzhou University
🇨🇳Zhengzhou, Henan, China
The First Affiliated Hospital of Zhengzhou University🇨🇳Zhengzhou, Henan, ChinaFei Xu, DoctorContact18623716648xu.fei@haut.edu.cn