The effect of intrauterine injection of human chorionic gonadotropin (hCG) before embryo transfer on the implantation and pregnancy rates in the intracytoplasmic sperm injection (ICSI)

Phase 2

• Conditions: Infertility.; In vitro fertilization

• Registration Number: IRCT2013060913605N1
• Lead Sponsor: Avicenna Infertility Clinic

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 121

Inclusion Criteria

Inclusion Criteria: age between 20 and 40 yr; infertility due to male factor, PCO, or with unknown cause; informed consent from couples; obtaining high quality embryos

Exclusion criteria: azoospermia or severe oligoasthenoteratospermia; previous successful or failed IVF/ICSI; myometrium or any uterus abnormality; previous myomectomy; moderate to severe endometriosis; hydrosalpynx; obtaining more than 20 ovums or probable OHSS; nonadherence to the study protocol

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Implantation rate. Timepoint: 2 weeks after embryo transfere. Method of measurement: Serum level of B-hCG (mIU/ml) based on laboratory report.;Pregnancy rate. Timepoint: 3 weeks after positive serum B-hCG. Method of measurement: Detection of gestational sac by ultrasonographic exam.

Secondary Outcome Measures

Name	Time	Method
Serum level of B-hCG. Timepoint: 2 weeks after embryo transfere. Method of measurement: mIU/ml based on laboratory report.