A low-intervention study to determine whether pre-exposure prophylaxis with low dose aerosol combination medication (ACM) can reduce SARS-CoV-2 incidence in healthcare workers exposed to routing COVID-19 positive contacts (LOWACM)

orth-Western State Medical University named after I.I. Mechnikov0 个研究点目标入组 99 人开始时间: 2020年9月14日最近更新: 2022年10月17日

试验速览

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34098889/ (added 09/06/2021)

•1. Willing and able to provide informed consent
•2. Aged 18-80 years
•3. Healthy volunteer
•4. Healthcare workers (HCWs) exposed to routine COVID-19 positive contacts
•5. Agrees to cooperate adequately to all aspects of the study, can understand the information provided about the study, and is willing to comply with the requirements of the study protocol

•1. Detection of SARS-CoV-2 virus RNA by polymerase chain reaction (PCR) in biomaterial samples and/or positive enzyme-linked immunosorbent assay ELISA IgM and ELISA IgG to the virus
•2. Hypersensitivity or individual intolerance to the components of the combination therapy according to medical history
•4. Criteria related to the concomitant pathology
•5. Obviously or likely unable to understand and evaluate the information regarding this study within the process of signing the informed consent form, in particular regarding the expected risks and possible discomfort
•6. The inability or unwillingness to follow the rules for carrying out the study and participating in the study

发起方

orth-Western State Medical University named after I.I. Mechnikov