跳至主要内容
临床试验/CTRI/2025/03/083686
CTRI/2025/03/083686尚未招募不适用

Evaluation of VEXUS score as a marker for acute kidney injury in patients of septic shock.

Max superspeciality hospital1 个研究点 分布在 1 个国家目标入组 82 人开始时间: 2025年4月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
82
试验地点
1
主要终点
1.Evaluation of utility of VEXUS score as a marker for acute kidney injury in patients with septic shock.

研究概览

简要总结

Septic shock is defined as a subset of sepsis in which particularly profound circulatory, cellular and metabolic abnormalities are associated with greater risk of mortality. Venous congestion is a promising physiological marker that may be able to help direct resuscitation of patients with septic shock. Venous congestion is an important haemodynamic state in sepsis patients because it is associated with impaired organ function, particularly acute kidney injury. Therefore, we intend to evaluate of VEXUS score as a marker for acute kidney injury in patients of septic shock.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 75.00 Year(s)(—)
性别
All

入选标准

  • Patients who fulfil the septic shock definition according to the Sepsis-3 consensus conference.

排除标准

  • Patient’s refusal to participate.
  • Patients in which more than 4 hours have elapsed since diagnosis of septic shock.
  • Anticipated to undergo immediate surgery.
  • Hemodynamic instability due to active haemorrhage.
  • Patients with previously known conditions that interfere with Doppler assessments, namely liver cirrhosis.
  • Pregnancy Chronic Kidney Disease (CKD) patients on Haemodialysis.

结局指标

主要结局

1.Evaluation of utility of VEXUS score as a marker for acute kidney injury in patients with septic shock.

时间窗: Will be observed till patient is admitted in intensive care unit.

次要结局

  • 1.Correlation of VEXUS score with need of renal replacement therapy in sepsis patients.(2.Correlation of VEXUS score with intensive care unit mortality.)

研究者

申办方类型
Research institution and hospital

研究点 (1)

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