EUCTR2008-006802-40-NO进行中（未招募）不适用
A PHASE II STUDY WITH OXALIPLATIN + 5FU + CETUXIMAB AND RADIOTHERAPY FOR TREATMENT OF NON-RESECTABLE, LOCALLY ADVANCED BUT NOT METASTATIC CANCER OF OESOPHAGUS OR THE CARDIA REGION - LERFOX-C
Akademiska University Hospital0 个研究点目标入组 90 人开始时间: 2012年6月28日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 90
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Histologically verified squamous cell carcinoma or adenocarcinoma of the oesophagus or cardia (Siewert I-II)
- •Performance status (WHO) 0-2, age 18-80 y
- •Locally advanced disease non-resectable (T4 N0-N3, M0) or disease which is not operable for any other reason (T2/T3 N0-N3, M0)
- •Adequate hematological, liver and renal function
- •Written informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Distant metastases
- •Prior chemotherapy or radiotherapy for oesophageal ca or ca of the cardia region
- •Symptomatic peripheral neuropathy equal to or greater than NCI grade 2
- •Other concomitant serious illness or medical condition that would not permit the patient to complete the study treatment or sign the informed concent
- •Myocardial infarction within 6 months prior to study entry
- •Second primary malignancy (except in situ carcinoma of the cervix or adequately treated basal cell carcinoma of the skin) unless treated, in remission and off active treatment for greater than 5 years
研究者
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