IRCT2015102316844N2
Completed
Phase 2
Comparison the effect of Topiramate and Amitriptyline Prophylactic therapy on cyclic vomiting syndrome in Pediatrics
Vice Chancellor for Research of Isfahan University of Medical Sciences0 sites60 target enrollmentTBD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Cyclical vomiting syndrome.
- Sponsor
- Vice Chancellor for Research of Isfahan University of Medical Sciences
- Enrollment
- 60
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Children 3\-15
- •years old with diagnosis of cyclic vomiting syndrome (based on Rome III criteria: 1 Stereotypical episodes of vomiting regarding onset (acute) and duration (less than 1 week); 2\) Three or more discrete episodes in the prior year; and 3\) Absence of nausea and vomiting between episodes and absence of metabolic, gastrointestinal, central nervous system structural or biochemical disorders); Normal Neurological and Developmental examination Exclusion criteria: Known metabolic disease; Obstructive disease of gastrointestinal or urinary system; Patients who don't give consent to participate in the study or want to leave the study anytime.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Not specified
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