Efficacy of Excimer Light(308) Therapy for Resistant Alopecia Areata
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 20
- 主要终点
- alopecia areata with ecimer light
研究概览
简要总结
This study aimed to evaluate the efficacy and safety of the 308-nm excimer lamp in resistant AA treated with topical minoxidil .
详细描述
Alopecia areata (AA) is a chronic, nonscarring, T-cell mediated autoimmune disease, presenting with localized or diffuse hair fall in hair-bearing areas. Approximately 1.7% of the population experience an episode of AA during their lifetime. Both sexes are equally affected, and most new cases are recorded below the age of 30 years . Excimer laser using high-dose monochromatic UV radiation can trigger apoptosis and induce immunological suppression through altering cytokine production such as IL-4, IL-10, prostaglandin E2, platelet-activating factor, and cis-urocanic acid. Benefits have only been seen with localized patches of AA, and regrowth of hair occurs only in treated areas .
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •● Having multiple patches of AA.
- •Duration of alopecia >1 year
- •No topical or systemic treatment for the last 4 months
- •Agreement to regular visits for treatment and follow-up.
排除标准
- •● A single form of AA.
- •Alopecia for <1 year.
- •Being on other modalities of treatment.
- •Treatment within the last 4 months.
- •Photosensitive disorders.
- •Pregnancy or breastfeeding.
结局指标
主要结局
alopecia areata with ecimer light
时间窗: 3 months
evulate patients monthly during treatment with excimer light and minoxidil gel for three months With 20 patients who should completely recovered from alopecia areata.
次要结局
未报告次要终点