Chewing Clopidogrel in Addition to Regular Oral Clopidogrel Treatment to Improve Platelets Aggregation in Patient With NON ST ELEVATION MI

Phase 3

• Conditions: Platlet Aggregation; Major Bleeding Outcomes
• Interventions: Drug: clopidogrel by chewing; Drug: Placebo

• Registration Number: NCT00889044
• Lead Sponsor: Sheba Medical Center

Brief Summary

Since the absorption of clopidogrel through the gastrointestinal tract is limited, we want to examine whether adding clopidogrel by chewing will overcome the limited gastrointestinal absorption, and hence will improve the prevention of platelet aggregation.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-04
• Study Start: 2009-04
• Study First Submitted: 2009-04-26
• Study First Submitted QC: 2009-04-26
• Last Update Submitted: 2009-04-26
• Study First Posted: 2009-04-28
• Last Update Posted: 2009-04-28
• Primary Completion: 2010-12
• Study Completion: 2011-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Male and Female older than 18 years old with non-ST myocardial infarction

Exclusion Criteria

• Current treatment with anticoagulation medication, any type of cerebro vascular event in the past, active bleeding, active peptic ulcer disease, pregnant women, any inability to sign an informed consent of participate in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
clopidogrel by chewing	clopidogrel by chewing	-
Placebo	Placebo	-

Primary Outcome Measures

Name	Time	Method
Platelet aggregation and bleeding events	6 months

Trial Locations

Locations (2)

Sheba_medical_center; 🇮🇱 Ramat-Gan, Israel

Sheba Medical Center, Cardiac Institute; 🇮🇱 Tel Hashomer, Israel