A romdomized controlled study of effectiveness between transcatheter arterial chemoembolization with cisplatin and transcatheter arterial chemoembolization with epirubicin for multiple hepatocellular carcinomas
- Conditions
- multiple hepatocellar carcinomas
- Registration Number
- JPRN-UMIN000003162
- Lead Sponsor
- Department of Surgery, Graduate School of Medicine Kyoto Uinversity
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 160
Not provided
1)Patients with another active cancer 2)Patients with extrahepatic metastasis 3)Patients with prior surgical reconstruction of the biliary tract or prior endoscopic treatment of ampulla of vater 4)Patients with clinically significant refractory ascites or pleural effusion 5)Patients with hepatic encephalopathy 6)Patients with severe co-morbidity such as cardiac failure and renal failure 7) Patients who have taken doses of chemotherapeutic agents with cardiac toxicity exceeding a set threshold. 8)Patients with a medical history of severe hypersensitivity 9)Patients who are pregnant, lactating or are suspected to be pregnant. 10)Patients who are concluded to be inappropriate to participate in this study by their physicians
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response rate(based on EASL criteria)
- Secondary Outcome Measures
Name Time Method Overall survival Progression free survival Response rate(based on the General Rules for the Clinical and Pathological Study of Primary Liver Cancer) Safety