Safety and Effectiveness of EKOS in PE Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 104
- 试验地点
- 1
- 主要终点
- The change in RV/LV diameter ratio
研究概览
简要总结
A retrospective cohort study assessed patients who underwent EKOS intervention following the failure of initial therapeutic anticoagulation for managing acute pulmonary embolism at a tertiary hospital.
详细描述
A retrospective cohort study assessed patients who underwent EKOS intervention following the failure of initial therapeutic anticoagulation for managing acute pulmonary embolism at a tertiary hospital. Patients aged at least 18 years with a diagnosis of submassive or massive acute PE were included. Patients were excluded if they either did not receive EKOS intervention or were presented with stable PE. The primary outcome was the change in RV/LV diameter ratio from baseline to first outpatient follow-up.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients ≥ 18 years diagnosed with massive or submassive acute PE.
排除标准
- •Patients presented with stable PE
- •Patients did not receive EKOS intervention.
研究组 & 干预措施
ECOS group
ECOS
干预措施: ECOS (Drug)
Control group
IV infusion tpa
干预措施: Control group (Drug)
结局指标
主要结局
The change in RV/LV diameter ratio
时间窗: one month
The change in RV/LV diameter ratio from baseline to first outpatient follow-up as documented on an echocardiogram.
次要结局
- All-cause 30-day readmission(one month)
研究者
Asmaa Abdelfattah Elsayed
Lecturer of clinical pharmacy
Beni-Suef University