Syndrome and Aspiration Pneumonia in Intensive Care
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- Determine the frequency of bacterial pneumonia in patients admitted to the ICU for coma and treated with mechanical ventilation
研究概览
简要总结
Inhalation is a common condition in patients with impaired their awareness requiring protection of the upper airway by endotracheal intubation. This inhalation may lead to chemical pneumonitis and/or bacterial pneumonia. Only the latter requires the administration of antibiotics. Patients developing such a bacterial pneumonia, has a mortality, duration of mechanical ventilation and length of ICU stay increased. However, the proportion of patients with such bacterial pneumonia, bacterial ecology and morbidity that are little known.
The aim of this study is to determine the frequency of bacterial pneumonia in patients admitted to the ICU for coma and treated with mechanical ventilation
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Altered consciousness defined by a Glasgow Coma Scale score less than or equal to 8 before protection of the upper airway by endotracheal intubation
- •Patient under mechanical ventilation
排除标准
- •Patient with pre-existing impairment of laryngeal function in Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, laryngeal cancer, radiotherapy laryngeal
- •Patient under guardianship
- •Inpatient without consent
- •Pregnant woman
- •Patient previously treated with antibiotics for more than 24 hours at the time of ICU admission
- •Patient with infection at ICU admission which justified probabilist antibiotic treatment
- •Lack of social security
- •Refusal of the patient or their next of kind
结局指标
主要结局
Determine the frequency of bacterial pneumonia in patients admitted to the ICU for coma and treated with mechanical ventilation
时间窗: ICU Discharge
Participants will be followed for the duration of ICU stay, an expected average of 4 days
次要结局
- Identification of predictive factors for development of bacterial pneumonia(ICU Discharge)
- Description of the bacterial flora identified in respiratory specimens.(ICU Discharge)
- Quantify the use of antibiotics during the ICU stay for patients admitted to the ICU for coma and treated with mechanical ventilation(ICU Discharge)