TCTR20240721002
Recruiting
Phase 4
Efficacy of botulinum toxin A for the management of melasma: A split-face, randomized control study
Division of Dermatology, Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand0 sites30 target enrollmentJuly 21, 2024
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Clinical diagnosis of melasma with symmetrical involvement of both malar areas
- Sponsor
- Division of Dermatology, Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
- Enrollment
- 30
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Age more than or equal to 18 years
- •2\. Clinical diagnosis of melasma with symmetrical involvement of both malar areas
- •3\. Willingness to comply with the study protocol and follow\-up visits
Exclusion Criteria
- •1\. Active skin infection or inflammation at the treatment sites
- •2\. Open wounds at the treatment sites
- •3\. Known allergy to study medications
- •4\. Neuromuscular disorders
- •5\. Uncontrolled acne vulgaris
- •6\. History of recurrent herpes infection
- •7\. Use of topical melasma treatments within 1 month or systemic/injectable treatments within 3 months
- •8\. Facial procedures (laser, dermabrasion, peeling, radiofrequency, micro\-focused ultrasound) within 6 months
- •9\. Facial botulinum toxin injections within 6 months
- •10\. pregnancy or lactation
Outcomes
Primary Outcomes
Not specified
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