“A PROSEPCTIVE CLINICAL STUDY TO ASSESS THE EFFECTIVENESS OF CONSTITUTIONAL HOMEOPATHIC MEDICINE IN CASES OF ECZEMA BETWEEN THE AGE OF 15-55 YEARS OF BOTH SEX BY USING THE ECZEMA AREA AND SEVERITY INDEX (EASI) SCALE”
Overview
- Phase
- Phase 1
- Status
- Not yet recruiting
- Sponsor
- SAINATH HOSPITAL
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Change in Eczema Area and Severity Index score from baseline to the end of the treatment.
Overview
Brief Summary
Eczema is a chronic, relapsing inflammatory skin disorder characterized by itching, redness, dryness, and lichenification, often causing considerable psychosocial distress. Conventional treatments such as corticosteroids and immunosuppressants may provide temporary relief but are associated with side effects and frequent relapses. Homeopathy, with its constitutional and holistic approach, aims to treat the individual as a whole, addressing not only the skin but also the mental and emotional spheres. This study seeks to scientifically evaluate the effectiveness of constitutional homeopathic medicines in eczema cases using the Eczema Area and Severity Index (EASI) as the assessment tool.
This prospective, clinical, interventional study will include 50 patients of both sexes aged 15–55 years, diagnosed with eczema. Case-taking will be performed as per Hahnemann’s guidelines (Organon aphorisms 83–104), followed by repertorization and prescription of individualized constitutional remedies. Patients will be followed up every 15 days for 12 months, and progress will be measured using the EASI scale.
The study aims to provide evidence on the role of constitutional homeopathy in improving the severity and extent of eczema, potentially offering a safe, effective, and holistic alternative to conventional therapy. By using a standardized scoring system, this research intends to bridge traditional homeopathic practice with objective clinical assessment.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- None
Eligibility Criteria
- Ages
- 15.00 Year(s) to 55.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •clinically diagnosed patients eczema based on EASI scale , both sex , between age of 15-55 , willing and able to give written informed consent.
Exclusion Criteria
- •Pt suffering from another skin diseases like psoriasis , lichen planus , tinea , bacterial and viral infections Autoimmune markers positive — suggests lupus or other autoimmune skin conditions.
- •Presence of systemic symptoms (like fever, weight loss) — might indicate more serious conditions.
- •Participants in another intervational study within the last 3 months.
- •Presence of serious comorbidities (eg.
- •Malignancy , uncontrolled diabetes , severe cardiac disease.
- •pregnant or lactating women.
Outcomes
Primary Outcomes
Change in Eczema Area and Severity Index score from baseline to the end of the treatment.
Time Frame: Change in Eczema Area and Severity Index score from baseline to the end of the treatment. | This measures the effectiveness of constitutional homeopathic medicine in reducing eczema severity.
This measures the effectiveness of constitutional homeopathic medicine in reducing eczema severity.
Time Frame: Change in Eczema Area and Severity Index score from baseline to the end of the treatment. | This measures the effectiveness of constitutional homeopathic medicine in reducing eczema severity.
Secondary Outcomes
- 1. Improvement in patient-reported symptoms using a Visual Analog Scale(2. Improvement in quality of life assessed by Dermatology Life Quality Index or similar questionnaire.)
Investigators
KANZARIYA NAVIN BHUPATBHAI
RAJKOT HOMEOPATHIC MEDICAL COLEGE