Use of Lumbar Drain to Remove Clots in Patients Admitted to the Neuro-ICU After Subarachnoid Hemorrhage.
Not Applicable
- Conditions
- Subarachnoid Hemorrhage.
- Registration Number
- NCT01886521
- Lead Sponsor
- Odense University Hospital
- Brief Summary
Recently, a clinical trial showed that the use of lumbar drains compared to ventricular drain in patients suffering from subarachnoid hemorrhage resulted in less delayed ischemic neurological deficits but failed to show a clinical benefit after 6 months. The underlying assumption was, that the cerebrospinal fluid (CSF) obtained from lumbar drains has a higher concentration of blood than CSF from lumbar drains. The investigators decided to test this assumption. In this study, the investigators will randomize patients to either placement of a ventricular or a lumbar drain and analyze the CSF drainage on a daily basis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- Patients admitted to the neuro-ICU with aneurysmal subarachnoid hemorrhage
- In need for CSF drainage based on clinical judgment
Exclusion Criteria
- intraventricular clots
- intraparenchymal clots causing midline shift
- pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Accumulated Hb and bilirubin in CSF drainage From drain placement to removal, in average 10 days.
- Secondary Outcome Measures
Name Time Method placement of a ventriculoperitoneal shunt participants will be followed for the duration of hospital stay, in average 3 weeks Lindegaard ratio (TCD) > 3 the participants will be followed for the duration of hospital stay, in average 3 weeks clinical signs of vasospasms The participants will be followedd for the duration of hospital stay, in average 3 weeks
Trial Locations
- Locations (1)
Department of Neurosurgery, Odense University Hospital
🇩🇰Odense, Denmark
Department of Neurosurgery, Odense University Hospital🇩🇰Odense, Denmark