Sex-Specific Environmental and Reproductive Health Risk Factors for Lewy Body Dementia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Lewy Body Dementia
- Sponsor
- University of California, San Diego
- Enrollment
- 225
- Locations
- 1
- Primary Endpoint
- Environmental, occupational, reproductive health factors
- Status
- Active, not recruiting
- Last Updated
- last year
Overview
Brief Summary
The goal of this survey study is to identify environmental, occupational and reproductive health risk factors for Lewy body dementia, which includes Parkinson's disease dementia and dementia with Lewy bodies. Participants will complete a one-time survey online or over the phone that includes questions on environmental, occupational factors they may have been exposed to and on medical history including reproductive health. Researchers will then compare the responses of people with Lewy body dementia and people without Parkinson's or memory/thinking problems to see which factors play a role in Lewy body dementia. Identifying risk factors can guide future treatment efforts and provide more insight to this dementia.
Detailed Description
Lewy body dementia, including Parkinson's disease dementia and dementia with Lewy bodies, is one of the most common dementias and does not have a cure for now. It can occur differently for women and men, although we are not sure why. The ratio of women to men for the disease prevalence changes with older age, suggesting a potential role for reproductive factors, particularly for women. Environmental factors impact the risk for other types of dementia, although such factors have not been clearly described in Lewy body dementia specifically. Women and men may get exposed to different environmental and occupational risk factors, and the impact of factors can differ for women and men. By using one-time survey that can be completed online or over the phone, we will try to understand which environmental, occupational or reproductive health factors play a role in Lewy body dementia for women and men. By comparing the survey responses of people with Lewy body dementia and people without Parkinson's or memory/thinking problems, we aim to identify specific risk factors for women and men that can guide future treatment efforts and provide more insight into this dementia.
Investigators
Ece Bayram
Principal Investigator
University of California, San Diego
Eligibility Criteria
Inclusion Criteria
- •For participants with Lewy body dementia: Clinical diagnosis of Lewy body dementia (Parkinson's disease dementia or dementia with Lewy bodies)
- •For controls: Normal cognition
- •Implication of consent to participate by stating consent verbally over the phone or by selecting the appropriate response on the online survey to indicate consent
Exclusion Criteria
- •For controls: Parkinson's disease or dementia diagnosis
Outcomes
Primary Outcomes
Environmental, occupational, reproductive health factors
Time Frame: 1 year
Responses of participants with Lewy body dementia and controls completing the survey including questions on environmental, occupational and reproductive health factors will be compared to determine which factors play a role in Lewy body dementia.