The Effect of Chewing Gum on Small Bowel Transit Time
Not Applicable
Completed
- Conditions
- Bowel Transit Times
- Registration Number
- NCT01241825
- Lead Sponsor
- University of British Columbia
- Brief Summary
The purpose of this study is to see if chewing sugarless chewing gum alters the time it takes for a capsule endoscopy to travel through the stomach and small bowel, and to see if more/less capsule endoscopes reach the large bowel.
- Detailed Description
The subjects will include patients already referred to us for a capsule endoscopy (CE) in this unit. We have calculated how many patients we need from small bowel transit times from the last 100 patients who had a CE at our centre. We will include 122. These will be randomly divided into two groups. The patients (chew chewing gum) and the controls (do not chew chewing gum).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 122
Inclusion Criteria
- All out-patients > 19 years old presenting for capsule endoscopy
Exclusion Criteria
- Patients on narcotics
- Patients on motility enhancing and/or slowing drugs should stop these at least 5 days prior to the procedure or be excluded from the study.
- Patients, who have proven or suspected obstruction of the bowel.
- Patients, who have had prior small bowel and/or gastric surgery.
- Patients with an ileostomy.
- Patients who have a known and/or have a history of swallowing disorder
- Patients with diabetes and/or hypo-/hyper- thyroidism
- Patients in whom the capsule become impacted at a stricture (these patients will be taken out of the study and given the necessary medical/surgical treatment).
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Small bowel transit time 6 hours
- Secondary Outcome Measures
Name Time Method Gastric transit time, cecal completion rate 6 hours
Trial Locations
- Locations (1)
St. Paul's Hospital
🇨🇦Vancouver, British Columbia, Canada
St. Paul's Hospital🇨🇦Vancouver, British Columbia, Canada