IRCT20090609002017N32已完成未知
Assessment of oleoylethanolamide supplementation on the expression of SIRT1, AMPK, PGC-1a, PPAR-?, CEBP-a, CEBP- ß, IL-6, and IL-10 genes, serum IL-6, IL-10, hs-CRP, IL-1ß, TNF-a, TAC, GSH-Px, SOD, catalase, MDA, ox-LDL, and NRG-4 levels, and body composition in obese patients with non-alcoholic fatty liver disease (NAFLD)
Vice chancellor for research , Tabriz University of Medical Sciences, Nutrition Research Center0 个研究点目标入组 60 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 years 至 50 years（—）
- 性别
- All
入选标准
- •Ages between 20 to 50 years
- •body mass index (BMI) 30 to 40 kg/m2
- •Diagnosis of non-alcoholic fatty liver disease by a liver specialist based on ultrasound
排除标准
- •Regular use of nonsteroidal anti-inflammatory agents (NSAIDs) and antibiotics
- •Use of hepatotoxic drugs such as phenytoin, amiodarone, levothyroxine, amoxifene, lithium
- •Use of antihypertensive drugs
- •Using weight loss and lipid-lowering drugs
- •Use of probiotic and prebiotic supplements; vitamins; minerals; antioxidants; and omega 3 supplements in the last 3 months
- •Breast-feeding
- •Pathological conditions affecting the liver such as viral hepatitis, acute or chronic hepatic impairment, liver transplantation, acute systemic disease
- •Gastrointestinal diseases
- •Heart failure
- •Thyroid disorders
- •Kidney Diseases
- •Haemochromatosis
- •Wilson's disease
- •Alpha-1 antitrypsin deficiency
- •Autoimmune diseases
研究者
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