MedPath

CS Scar Impact on ART Outcomes

Recruiting
Conditions
Fertility Issues
Registration Number
NCT06021886
Lead Sponsor
HealthPlus Fertility Center
Brief Summary

CS scar impact on ART outcomes, Retrospective Cohort Study IVF outcome can be affected by the presence of caesarean section scar with or without defect in different ways

Detailed Description

CS scar impact on ART outcomes, Retrospective Cohort Study IVF outcome can be affected by the presence of caesarean section scar with or without defect in different ways; increase difficulty of embryo transfer, presence intrauterine fluid at the time of transfer can affect the chances of embryo implantation and increase the rate of spontaneous miscarriages To compare the success rates and outcomes of pregnancies of frozen embryo transfer for euploid embryos in patients without caesarean section, and who had caesarean section (with or without a NICHE) after euploid embryo transfer. Does CS scar and CS scar defect affect IVF outcome? All women who underwent an embryo transfer with a Euploid embryo between 2015 and 2022, who meet the inclusion criteria will be included in the study.

* Inclusion Criteria: Age 25-40 years old. Euploid embryo transfer. Medically free BMI less tha 30 kg/m2 Hormone therapy preparation for FET.

* Exclusion criteria Previous uterine scar other than cesarean section. Congenital uterine abnormalities Presence of intrauterine lesions e.g., polyp, fibroid, Endometriosis or adenomyosis Hydrosalpinx, Chronic endometritis

* Primary outcome: Clinical pregnancy rate, defined as a pregnancy with a detectable heart rate at 7 weeks of gestation or beyond.

* Secondary outcomes : Early pregnancy complications Ectopic pregnancy or Miscarriage. Caesarean section scar dehiscence or

Recruitment & Eligibility

Status
RECRUITING
Sex
Female
Target Recruitment
510
Inclusion Criteria
  • Age 25-40 years old.

Euploid embryo transfer.

Medically free

BMI less tha 30 kg/m2

Hormone therapy preparation for FET.

Exclusion Criteria
  • Exclusion criteria

Previous uterine scar other than cesarean section.

Congenital uterine abnormalities

Presence of intrauterine lesions e.g., polyp, fibroid,

Endometriosis or adenomyosis

Hydrosalpinx, Chronic endometritis

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
CS scar impact on ART outcomes, Retrospective Cohort Study2015 to 2022,

Clinical pregnancy rate

Secondary Outcome Measures
NameTimeMethod
ART outcomes2015 to 2022,

Early pregnancy complications:

Ectopic pregnancy or Miscarriage.

Caesarean section scar dehiscence or rupture.

Presence of intrauterine fluid accumulation at the time of ET.

Endometrial thickness at the time of ET.

Live birth.

Trial Locations

Locations (1)

HealthPlus fertility Centre

🇦🇪

Abu Dhabi, United Arab Emirates

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