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临床试验/NCT06021886
NCT06021886招募中不适用

CS Scar Impact on ART Outcomes

HealthPlus Fertility Center1 个研究点 分布在 1 个国家目标入组 510 人开始时间: 2023年6月15日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
510
试验地点
1
主要终点
CS scar impact on ART outcomes, Retrospective Cohort Study

研究概览

简要总结

CS scar impact on ART outcomes, Retrospective Cohort Study IVF outcome can be affected by the presence of caesarean section scar with or without defect in different ways

详细描述

CS scar impact on ART outcomes, Retrospective Cohort Study IVF outcome can be affected by the presence of caesarean section scar with or without defect in different ways; increase difficulty of embryo transfer, presence intrauterine fluid at the time of transfer can affect the chances of embryo implantation and increase the rate of spontaneous miscarriages To compare the success rates and outcomes of pregnancies of frozen embryo transfer for euploid embryos in patients without caesarean section, and who had caesarean section (with or without a NICHE) after euploid embryo transfer. Does CS scar and CS scar defect affect IVF outcome? All women who underwent an embryo transfer with a Euploid embryo between 2015 and 2022, who meet the inclusion criteria will be included in the study.

  • Inclusion Criteria: Age 25-40 years old. Euploid embryo transfer. Medically free BMI less tha 30 kg/m2 Hormone therapy preparation for FET.
  • Exclusion criteria Previous uterine scar other than cesarean section. Congenital uterine abnormalities Presence of intrauterine lesions e.g., polyp, fibroid, Endometriosis or adenomyosis Hydrosalpinx, Chronic endometritis
  • Primary outcome: Clinical pregnancy rate, defined as a pregnancy with a detectable heart rate at 7 weeks of gestation or beyond.
  • Secondary outcomes : Early pregnancy complications Ectopic pregnancy or Miscarriage. Caesarean section scar dehiscence or

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
25 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Age 25-40 years old.
  • Euploid embryo transfer.
  • Medically free
  • BMI less tha 30 kg/m2
  • Hormone therapy preparation for FET.

排除标准

  • Exclusion criteria
  • Previous uterine scar other than cesarean section.
  • Congenital uterine abnormalities
  • Presence of intrauterine lesions e.g., polyp, fibroid,
  • Endometriosis or adenomyosis
  • Hydrosalpinx, Chronic endometritis

结局指标

主要结局

CS scar impact on ART outcomes, Retrospective Cohort Study

时间窗: 2015 to 2022,

Clinical pregnancy rate

次要结局

  • ART outcomes(2015 to 2022,)

研究者

发起方
HealthPlus Fertility Center
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ahmed Elsayed Hassan Hamed Elbohoty

Reproductive medicine consultant

HealthPlus Fertility Center

研究点 (1)

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