Clinical Empirical Research of ARDS

Chinese PLA General Hospital1 个研究点分布在 1 个国家目标入组 200 人2023年6月18日

适应症Invasive Mechanical Ventilation ARDS

概览

阶段: 不适用
干预措施: 未指定
疾病 / 适应症: Invasive Mechanical Ventilation ARDS
发起方: Chinese PLA General Hospital
入组人数: 200
试验地点: 1
主要终点: Overall Survival
状态: 招募中
最后更新: 2年前

概览研究者入排标准结局指标研究点相似试验

概览

简要总结

According to the ARDS Berlin definition, patients with severe concurrent invasive mechanical ventilation were selected, and clinical data and prognosis were collected. Samples such as blood and balf were collected for analysis based on changes in the condition.

注册库

clinicaltrials.gov

开始日期

2023年6月18日

结束日期

2026年6月1日

最后更新

2年前

研究类型

Observational

性别

All

研究者

发起方

Chinese PLA General Hospital

责任方

Principal Investigator

主要研究者

wang kaifei

Chinese PLA General Hospital

入排标准

入选标准

•Patients who meet the Berlin definition of ARDS and require invasive mechanical ventilation. ARDS diagnostic criteria: according to the Berlin definition, Chest radiograph shows patchy shadows in the lungs; Respiratory failure cannot be completely caused by heart failure or excessive fluid infusion
•ARDS onset ≤ 3 days when included in the study
•Patient PaO2/FiO2 ≤ 200mmHg when included in the study

排除标准

•Patients with intracranial hypertension, pleural fistula, pneumothorax, HIV, HBV, HCV
•Age\>85 years old or\<18 years old
•Pregnant patients
•Severe hemodynamic instability (vasopressor increase\>30% in the first 6 hours, or Norepinephrine\>0.5 mg kg/min)
•Patients unable to perform EIT ventilation and/or perfusion testing (unable to perform internal jugular vein catheterization, Hypernatremia, chest malformation, active implant device, unstable spinal injury or fracture, skin lesions opposite the EIT monitoring area)
•Patients with abnormal esophageal anatomical structure and inability to indwelling gastric tubes
•Disagreement for inclusion in this study