Microemboli in Aortic Valve Surgery: Minimized Extracorporeal Circulation vs. Classic Extracorporeal Circulation.

Completed

• Conditions: neurocognitive deficit; Stroke; 10046973; 10009841; 10003184

• Registration Number: NL-OMON33526
• Lead Sponsor: Sint Antonius Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

1.The patient must be between 18-80 years of age.
2.Patients scheduled for elective aortic valve surgery or combined coronary with aortic valve surgery
3.The patient is mentally able and willing to give informed consent.

Exclusion Criteria

1. Emergency operation
2. Active endocarditis
3. Double valve procedure.
4. Operation on the aortic root.
5. Very poor left ventricular function (EF < 20 %).
6. Previous cardiac surgery.
7. Dialysis dependent renal failure.
8. Internal carotid artery stenosis of 50% or greater.
9. Illeracy or nonfluency in dutch.
10. Absence of aucoustic window for TCD monitoring
11. Contraindications for MRI (electronically, magnetically, and mechanically activated implants [Pacemaker,nervestimulator, Insulin pumps etc], metallic splinters, claustrophobia, cochlear implants and ferromagnetic mechanical stapedial replacements, clips in the central nervous system (CNS) ).

Study & Design

• Study Type: Interventional
• Study Design: Not specified