Diet Composition - Metabolic Regulation and Long-term Compliance
Not Applicable
Completed
- Conditions
- Obesity
- Registration Number
- NCT00692536
- Lead Sponsor
- Umeå University
- Brief Summary
This study will compare a high-protein/low-carbohydrate diet (modified paleolithic diet, MPD) with a diet high in slow carbohydrates (Nordic Nutrition Recommendations, NNR). The diets will be compared with respect effects on weight reduction, metabolic regulation, and long-term compliance to the diet regimes. Seventy-two postmenopausal overweight healthy women have been recruited and will be followed for two years.
The following variables will be studied:
* Anthropometry
* DEXA
* OGTT
* Liver fat content measured with 1H-MRS
* Hepatic 11β-HSD1 activity, measured with cortisone/cortisol conversion test
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 70
Inclusion Criteria
- Female
- Postmenopausal
- BMI>28
Exclusion Criteria
- Disease
- Gravidity
- Smoking
- Prescribed medication
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Liver fat Sept 2008
- Secondary Outcome Measures
Name Time Method Apnea-Hypopnea Index (AHI) Sept 2008 Body weight Sept 2008
Trial Locations
- Locations (1)
Umeå University
🇸🇪Umeå, Sweden
Umeå University🇸🇪Umeå, Sweden