NCT00692536已完成不适用
Diet Composition - Metabolic Regulation and Long-term Compliance
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Liver fat
研究概览
简要总结
This study will compare a high-protein/low-carbohydrate diet (modified paleolithic diet, MPD) with a diet high in slow carbohydrates (Nordic Nutrition Recommendations, NNR). The diets will be compared with respect effects on weight reduction, metabolic regulation, and long-term compliance to the diet regimes. Seventy-two postmenopausal overweight healthy women have been recruited and will be followed for two years.
The following variables will be studied:
- Anthropometry
- DEXA
- OGTT
- Liver fat content measured with 1H-MRS
- Hepatic 11β-HSD1 activity, measured with cortisone/cortisol conversion test
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- None
入排标准
- 年龄范围
- — 至 70 Years（Child, Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Postmenopausal
排除标准
- •Gravidity
- •Prescribed medication
研究组 & 干预措施
1
Active Comparator
NNR
干预措施: NNR (Nordic Nutrition Recommendations) (Behavioral)
2
Active Comparator
MPD
干预措施: MPD (Modified paleolithic diet) (Behavioral)
结局指标
主要结局
Liver fat
时间窗: Sept 2008
次要结局
- Body weight(Sept 2008)
- Apnea-Hypopnea Index (AHI)(Sept 2008)
研究者
研究点 (1)
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