A Randomized Control Trial on effect of Halotherapy in improving airway clearance among patient with COPD admitted in selected tertiary care hospital of Western Maharashtra.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- improvement in breathing pattern
研究概览
简要总结
Hypertonic saline nebulization therapy Procedure: Random sampling of patients will be done. On admission mortality assessment will be done by DECAF score. Sample will be equally divided into 2 groups (Intermediate & High risk). Random sampling will be done to devide them in experimental and control grop.Experimental group will be administered 3% hypertonic saline nebulisation after routine broncodilator neblisation for 10 mins 6 hrly in a day for 07 days and control group will receive routine broncodilator neblisation treatment of exacerbation of COPD. Both groups will have control and experimental group. Groups will be assessed by modified borg scale, peak flow, duration of hospital stay, need of invasive ventilation & 30 day mortality with Spirometry, pulse oximetry, heart rate recording & respiratory rate recording to ensure the evidence of bronchospasm. Both the pre intervention and post intervention scores will be entered in coding sheet.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 16.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •All patients previously diagnosed with COPD and presently admitted with acute exacerbation having intermediate to high risk as per DECAF score.
排除标准
- •Patients with history of hospitalization in last 90 days.
- •Patients requiring invasive mechanical ventilation within 48 hours of hospitalization.
- •Patient with asthma COPD overlap and COPD bronchiectasis overlap.
- •• Non- consenting patients • Patient allergic to Sodium Chloride.
- •• Patient geting other mucoactive substance other than standard treatment.
结局指标
主要结局
improvement in breathing pattern
时间窗: after 7 days therapy
Improvement in peak flow
时间窗: after 7 days therapy
次要结局
未报告次要终点
研究者
TULIKA DE BISWAS
College of Nursing, Armed Forces medical College & Hospital
