Rapid Non-Invasive Brain Stimulation for Hoarding Disorder
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Change in Compulsive Acquisition Scale (CAS)
研究概览
简要总结
This study explores whether rapid non-invasive brain stimulation can help reduce hoarding disorder symptoms.
详细描述
Hoarding disorder (HD) is characterized by difficulty letting go of possessions, leading to clutter that congests living spaces and impairs daily functioning. The majority of HD patients treated with cognitive behavioral therapy for HD usually experience considerable residual symptoms. New treatments are greatly needed. This study explores whether rapid non-invasive brain stimulation can help reduce hoarding disorder symptoms.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-70 years
- •Primary diagnosis of hoarding disorder
- •Sufficient severity of hoarding symptoms
- •Willing and able to understand and complete consent and study procedures
排除标准
- •Psychiatric or medical conditions or medications that make participation unsafe
- •Pregnant or nursing females
- •Previous exposure to TMS or ECT
- •History of any implanted device or psychosurgery
研究组 & 干预措施
Theta-burst stimulation (TBS)
Theta-burst stimulation (a form of transcranial magnetic stimulation) targeting the right frontal pole.
干预措施: MagPro X100 by MagVenture (Device)
结局指标
主要结局
Change in Compulsive Acquisition Scale (CAS)
时间窗: Change from baseline to 3 weeks after treatment starts
The Compulsive Acquisition Scale (CAS) is an 18-item questionnaire that measures the extent to which individuals acquire and feel compelled to acquire possessions. The total score (sum of 18 items) ranges from 0 to 126. Total score higher than 48 shows significant difficulty with acquiring.
次要结局
未报告次要终点
研究者
Carolyn Rodriguez
Professor
Stanford University