Efficacy of sodium nitroprusside in the treatment of drug-naive subjects in first episode psychosis - an open label study

Phase 2

Recruiting

• Conditions: Regarding the design, this will be an open, non-randomized study.

• Registration Number: JPRN-UMIN000033473
• Lead Sponsor: Sinapse Bairral Research Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-01-01
• Study Completion: 2019-01-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

Not provided

Exclusion Criteria

Presence of relevant medical condition (cardiovascular diseases, neurological diseases, renal failure, liver disease, hypothyroidism, hyponatremia, hypovitaminosis B12, pregnancy, breastfeeding) or established and diagnosed organic frameworks. History of hypersensitivity to sodium nitroprusside. Diagnosis of substance abuse or dependence according to DSM-IV-TR criteria.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluation of positive symptoms using the PANSS scale. Before the procedure and after 24 hours

Secondary Outcome Measures

Name	Time	Method
Evaluation of negative symptoms, mania and general psychopathology, as well as side effects and tolerance. Using the PANSS and EACA-M scales.