Corneal Topographer Fluorescein Patterns

Completed

• Conditions: Keratoconus

• Registration Number: NCT00584285
• Lead Sponsor: Christine Sindt

Brief Summary

The objective of this study is to determine if corneal topography can be used to predict the fluorescein pattern of keratoconus lenses on the eye. A corneal topography image will be taken and the computer selected lens will be placed on the eye. After placement of the lens color photographs will be taken of the eye's fluorescein pattern and compared to the computer predicted pattern.

Detailed Description

Subject population: keratoconus patients who have not undergone corneal surgery 100 subjects who come to UIHC for their contact lens care. We will approach them at their visit. We will not call potential participants from a database.

If topography is impossible to capture. Concommitant Corneal Disease Minors will be excluded

Study Timeline

• Study Start: 2007-09-15
• Study First Submitted: 2007-12-21
• Study First Submitted QC: 2007-12-21
• Study First Posted: 2008-01-02
• Primary Completion: 2009-09-04
• Study Completion: 2009-09-14
• Results First Submitted: 2017-03-31
• Status Verified: 2018-03
• Results First Submitted QC: 2018-03-07
• Last Update Submitted: 2018-03-07
• Results First Posted: 2018-11-02
• Last Update Posted: 2018-11-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

18 yrs of age or older with diagnosis of keratoconus and contact lens wearer

Exclusion Criteria

Noncommittant corneal disease or surgery Inability to capture topography measurement

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of Participants With an Observable Difference Between Virtual Versus Actual Fluorescein Patterns	Baseline first visit	Comparison of fluorescein patterns of rgp contact lens. Bearing and elevation fluorescein patterns will be compared between the actual (photo) and theoretical (computer generated) fluorescein patterns using standard clinical means.

Trial Locations

Locations (1)

University of Iowa Hospitals and Clinics - Dept. of Ophthalmology; 🇺🇸 Iowa City, Iowa, United States