Effectivity and Safety of Ultrasound-guided Percutaneously Laser Ablation for Refractory Neoplasms
Phase 1
- Conditions
- Refractory Neoplasms
- Registration Number
- NCT02822053
- Lead Sponsor
- First Affiliated Hospital of Zhejiang University
- Brief Summary
The purpose of this study is to evaluate the safety and efficacy of ultrasonography (US) -guided laser ablation liver, kidney, pancreas, lung and retroperitoneal tumors, the investigators used preoperative and postoperative US/CEUS/CT/MRI to assess lesions, and laboratory tests including the tumor markers to evaluate the general condition of patients. Intraoperative US/CEUS/CT would be applied to monitor ablation lesions.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- Patients with small hepatocellular carcinoma (single or multiple nodules of less than 3 cm in diameter),
- Patients with Child-Pugh A/B,
- Patients with PLT ≥ 50*10E9/L and PT ≤ 20s.
Exclusion Criteria
- Patients with blood coagulation dysfunction, ChildPugh ≥3, severe cardiopulmonary disease, intolerant anesthesia and upper gastrointestinal bleeding in shock.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method 100 patients of refractory neoplasms with image-guided laser ablation-related effectivity as assessed by MRI up to 24 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
The First Affiliated Hospital of Zhejiang University
🇨🇳Hangzhou, Zhejiang, China
The First Affiliated Hospital of Zhejiang University🇨🇳Hangzhou, Zhejiang, ChinaTian'an Jiang, PhdContact+86 18857127666tiananjiang@126.comGuo Tian, MasterContact+86 13600529967871035504@qq.com