ACTRN12611000497909
Completed
Phase 4
A randomised double-blind placebo-controlled trial to investigate whether paracetamol lengthens the duration of viral shedding in the treatment of patients with influenza
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Medical Research Institute of New Zealand
- Enrollment
- 80
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Onset of an influenza like illness in the past 48 hours: history of fever or documented temperature greater than or equal to 37\.8 degree celsius, and at least one of cough, sore throat, rhinorrhea, headache, myalgia, fatigue, or malaise
Exclusion Criteria
- •Influenza illness severe enough to warrant hospital admission.
- •A history of allergy or sensitivity or other contraindication to paracetamol or opiates.
- •Subjects using paracetamol or NSAIDS (not including low dose aspirin) regularly who are unwilling or unable to discontinue use during the trial period.
- •Recent treatment with oseltamivir.
- •HIV infection.
- •Current pregnancy.
- •Current treatment with oral corticosteroids or other immunosuppressant drugs.
- •Any other safety concern at the investigator’s discretion.
Outcomes
Primary Outcomes
Not specified
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