A randomised placebo-controlled trial to investigate the use of paracetamol in the treatment of influenza

Phase 4

Completed

• Conditions: Influenza infection; Public Health - Other public health; Infection - Other infectious diseases

• Registration Number: ACTRN12611000497909
• Lead Sponsor: Medical Research Institute of New Zealand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-05-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Onset of an influenza like illness in the past 48 hours: history of fever or documented temperature greater than or equal to 37.8 degree celsius, and at least one of cough, sore throat, rhinorrhea, headache, myalgia, fatigue, or malaise

Exclusion Criteria

Influenza illness severe enough to warrant hospital admission.
A history of allergy or sensitivity or other contraindication to paracetamol or opiates.
Subjects using paracetamol or NSAIDS (not including low dose aspirin) regularly who are unwilling or unable to discontinue use during the trial period.
Recent treatment with oseltamivir.
HIV infection.
Current pregnancy.
Current treatment with oral corticosteroids or other immunosuppressant drugs.
Any other safety concern at the investigator’s discretion.

Study & Design

• Study Type: Interventional
• Study Design: Not specified