RECUCTION IN PAIN BY PREGABALIN, LIGNOCAINE OR COMBINATION OF BOTH IN RESPONSE TO INJECTION ROCURONIUM GIVEN DURING GENERAL ANAESTHESIA
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Patients undergoing elective surgeries under general anaesthesia.
- Registration Number
- CTRI/2018/06/014516
- Lead Sponsor
- Dr RPGMC Kangra at Tanda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
1. ASA class I-II
2. BMI 18.5-29.9
3. Undergoing elective surgeries under general anaesthesia.
Exclusion Criteria
1. Patientâ??s refusal for general anaesthesia
2. Neurological deficits
3. Pregnancy
4.Anticipated difficult intubation or difficult mask ventilation
5. BMI > 30.0
6. Those receiving long analgesics, sedatives, hypnotics, antidepressants
7. Hemodynamic instabilities during induction
8. Patients allergic to study drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the effects of Pregabalin, Lignocaine and combination of Pregabalin and Lignocaine in Rocuronium induced pain and WithdrawalTimepoint: 24 hours
- Secondary Outcome Measures
Name Time Method Hemodynamic parameters changesTimepoint: 24 hours;Intensity of pain using NRS during injection Rocuronium in sub-anaesthetic doseTimepoint: 60 seconds;Withdrawal response during injection Rocuronium in intubating doseTimepoint: 60 seconds;Withdrawal response during injection Rocuronium in sub-paralytic doseTimepoint: 60 seconds