Comparison of intravenous and nebulised routes of dexmedetomidine as premedication on surgical field visualisation in functional endoscopic sinus surgeries : a randomised control trial

Completed

• Conditions: Nasal polyp, (2) ICD-10 Condition: J31||Chronic rhinitis, nasopharyngitisand pharyngitis, (3) ICD-10 Condition: J32||Chronic sinusitis, (4) ICD-10 Condition: J34||Other and unspecified disorders ofnose and nasal sinuses, (5) ICD-10 Condition: J01||Acute sinusitis, (6) ICD-10 Condition: J30||Vasomotor and allergic rhinitis, (7) ICD-10 Condition: O||Medical and Surgical,

• Registration Number: CTRI/2023/05/052754
• Lead Sponsor: All India Institute of Medical Sciences, Bathinda

Brief Summary

In this study, we are comparing the comparing the effect of dexmedetomidine given as a premedication by different routes such as nebulisation and intravenous routes on the surgical field visualisation during functional endoscopic sinus surgeries.

although many studies have compared the efficacy of intravenous and nebulised dexmedetomidine separately, we would like to compare both the routes and would like to see which route is as better than the other or if there is no significant difference between two routes.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-06-15
• Study Completion: 2024-03-13
• Last Update Posted: 2024-07-05

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 114

Inclusion Criteria

American society of anaesthesiologists physical status 1 to 2 scheduled for elective functional endosocopic sinus surgeries under general anaesthesia.

Exclusion Criteria

• Patients not giving consent 2.
• Patient with body mass index ≥ 35 kg/m2.
• Pregnant patients 4.
• Patients who are allergic to any study drug 5.
• Patients with moderate-severe cardiovascular, respiratory, renal or hepatic impairment.
• • Patients with anticipated difficult airway • Patients who are smokers (more than 10 pack-years) • Patients with bleeding diathesis • Patients taking any type of BP controlling drugs.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Surgical field visualisation	till the end of surgery

Secondary Outcome Measures

Name	Time	Method
Hemodynamic changes, post-operative sore throat, post-	operative nausea & vomiting and sedative effect will be observed

Trial Locations

Locations (1)

AIIMS Bathinda; 🇮🇳 Bathinda, PUNJAB, India

AIIMS Bathinda

🇮🇳Bathinda, PUNJAB, India

Dr Hemanthkumar

Principal investigator

7845567680

abi.hemanthkumar@gmail.com