Effects of Balance Exercises on Central Sensitization in Patients With Knee Osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Central Sensitization Inventory (CSI)
研究概览
简要总结
The stimuli that activate nociceptors cause the dorsal horn of the spinal cord neurons to be sensitive to low-intensive afferent stimuli by decreasing the excitation threshold in patients with osteoarthritis. Although painful stimuli disappear, this situation causes pain to continue and a decrease in quality of life. Therefore, central sensitization should be considered and treated in patients with osteoarthritis. Although various pharmacological and electrophysiological agents are used in the treatment of central sensitization, adequate efficacy is not provided in patients with osteoarthritis. The aim of this study is to investigate the effects of balance exercises on central sensitization in patients with knee osteoarthritis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Being diagnosed with primary knee osteoarthritis according to American College of Rheumatology criteria,
- •To be stage 2-3-4 knee osteoarthritis according to Kellgren Lawrence radiological staging,
- •To be with a central sensitization score of over 40 according to the CSI,
- •To be able to fill the scales and accept to participate in the study.
排除标准
- •Being diagnosed with secondary osteoarthritis or inflammatory rheumatic disease,
- •Having cognitive impairment,
- •To have been treated with physiotherapy, with an intra articular injection or with a surgery from the knee within a maximum of six months
- •Having various diseases that may adversely affect performing balance exercises,
结局指标
主要结局
Central Sensitization Inventory (CSI)
时间窗: Before intervention, change in CSI scores at sixth week, change in CSI scores at 3 months.
CSI consists of 2 parts as A and B. Part A contains 25 items associated with central sensitization symptoms, and the person is asked to score each item between 0 (never) and 4 (always) and total score ranges from 0-100. It is accepted that there is central sensitization in individuals over 40 points. Part B consists of 10 diseases. In this section, it is questioned whether she was diagnosed one or more of these 10 diseases. If any of these diseases exist, the person is excluded from the study.
次要结局
- Western Ontario ve McMaster University Osteoarthritis Index (WOMAC)(Before intervention, change in WOMAC scores at sixth week, change in WOMAC scores at 3 months.)
- Berg Balance Scale (BBS)(Before intervention, change in BBS scores at sixth week, change in BBS scores at 3 months.)
- Y Balance Test(Before intervention, change in Y balance test scores at sixth week, change in Y balance test scores at 3 months.)
研究者
Emre Tirasci
Principal Investigator
Cukurova University