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A Clinical trial of CV-HFT01 tablets as Adjuvant Therapy in patients with hypothyroidism

Phase 1
Conditions
Health Condition 1: E039- Hypothyroidism, unspecified
Registration Number
CTRI/2019/04/018564
Lead Sponsor
Climic Health Pvt Ltd
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Closed to Recruitment of Participants
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Male and Female subjects of age 18 to 50 years (both inclusive) and willing to give written inform Consent

2. No Significant Medical History

3. Ability to understand the risks and benefits of the protocol

4. Subject With T3, T4 within Normal Range and TSH to be more than normal ( >4.5 u IU/L < 10 u IU/L) and with or without receiving on-going conventional medication for the same.

Exclusion Criteria

1.Women with a partial or complete hysterectomy, tubal ligations history

2.Women who are pregnant or lactating

3.Smokers/Alcoholics and/or drug abusers

4.Patient with poorly controlled Hypertension

5.Patients with evidence of malignancy

6.Patients receiving any herbal, Ayurvedic, homeopathic, siddha or unani medicine for hypothyroidism

7.History or presence of any medical condition or disease according to the discretion of the Investigator

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To assess improvement in T3 T4 & TSH levels from screening to end of treatmentTimepoint: Screening Visit , Visit 1 (Day 30) Visit 2 (Day 60) Visit 3 (Day 90)
Secondary Outcome Measures
NameTimeMethod
1.Improvement in subjective assessment of clinical symptoms like changes in body weight, anxiety, fatigue and excessive sweating related to hypothyroidism. <br/ ><br>2.To evaluate tolerability and safety of CV-HFT01 tablets in patients with hypothyroidism <br/ ><br>Timepoint: Screening Visit , Baseline Visit Visit 1 (Day 30) Visit 2 (Day 60) Visit 3 (Day 90)
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