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Clinical Trials/NCT03519789
NCT03519789
Completed
Not Applicable

Cognitive and Emotional Factors in Visual Exploration Among Patients With Post-Traumatic Stress Disorder

University Hospital, Lille1 site in 1 country80 target enrollmentMay 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Post-Traumatic Stress Disorder
Sponsor
University Hospital, Lille
Enrollment
80
Locations
1
Primary Endpoint
Response time before the detection of neutral and emotional stimuli.
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

Post-traumatic stress disorder (PTSD) is characterized by hypervigilance. In particular, previous works suggest that patients tend to scan constantly the environment for possible threats. The present project aims at investigating such attentional bias in patients with PTSD using the change blindness paradigm that offers the interesting possibility of studying sensitivity to sudden changes using ecological stimuli. More precisely, the investigators will investigate whether patients are more sensitive than matched controls to sudden changes in the visual environment and whether this hypersensitivity is specific or even stronger when visual information has an emotional content. The attentional bias will be measured using motor responses (accuracy and speed to indicate the occurrence of a change by pressing a button) as well as eye movements.

Registry
clinicaltrials.gov
Start Date
May 2014
End Date
May 5, 2020
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
University Hospital, Lille
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • a diagnosis of PTSD based on the standard DSM-IV criteria,
  • normal or corrected vision.
  • clinically stable at the testing time

Exclusion Criteria

  • history of neurological illness or trauma that occurred in the previous six months, - pregnant and nursing women,
  • drugs use in the last 24 hours,
  • an acute ocular disorder.
  • Participants will not be under tutorship, curatorship or deprived of liberty.

Outcomes

Primary Outcomes

Response time before the detection of neutral and emotional stimuli.

Time Frame: Baseline: one session

The explicit response of the participants will be measured with the response time before the detection of neutral and emotional stimuli.

Secondary Outcomes

  • Number of correct detections compared with the missed detections and false alarms.(Baseline: one session)
  • Total duration until the participant first fixed on a ROI.(Baseline: one session)

Study Sites (1)

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