Affection on Anastomotic Blood Flow and the Lymph Nodes Dissection Between Division at the Root of the Inferior Mesenteric Artery and Preserving the Left Colic Artery in Rectum Cancer Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 57
- 试验地点
- 1
- 主要终点
- The Blood Pressure of the Arterial Arcade
研究概览
简要总结
To evaluate the influence to the blood supply of the anastomosis and the harvest of the No. 253 lymph nodes in different surgical methods--- preserving the left colic artery (LCA) and resect the No. 253 lymph node specifically in the radical resection of rectal carcinoma or dividing at the root of the inferior mesenteric artery (IMA) in the radical resection of rectal carcinoma.
详细描述
Methods: The patients who got rectal carcinoma are divided into two groups. Both groups will receive the radical resection of rectal carcinoma. We preserve the left colic artery and resect the No. 253 lymph node specifically in Group A and divide at the root of the inferior mesenteric artery in Group B, We insert a trocar into the arterial arcade at the proximal site of the anastomosis and measure the blood pressure of the arterial arcade in the operation, which can reflect the blood supply of the anastomosis. Besides, We will measure the length of the colon from the anastomosis to the level of the root of the IMA. Expecting Results：The blood pressure of the arterial arcade in Group A will be higher than that in Group B. And the patients in Group A will have less chance to get anastomotic fistula. Expecting Conclusions: Preserving the LCA and resecting the No. 253 lymph node specifically in the radical resection of rectal carcinoma can improve the blood supply of the anastomosis and decrease the incidence of anastomotic fistula, and won't affect the harvest of the No. 253 lymph node.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients coming to FirstJilinU diagnosed rectum cancer by endoscopy and pathology.
- •The rectum cancer is the first malignant neoplasm the patient has got.
- •The cancer is solitary, and is 3cm to 20cm to the anus.
- •The surgical method is limited to Dixon.
排除标准
- •Being in the acute phase of inflammation before operation and emergency surgery.
- •Patients receiving steroid medication or preoperative radiotherapy。
- •Discovering macrometastasis before or in the operation.
- •The rectum cancer that can't be radical resected.
研究组 & 干预措施
preserving the left colic artery
We preserve the left colic artery and resect the No. 253 lymph node during the rectal surgery.
干预措施: preserving the left colic artery (Procedure)
not preserving the left colic artery
We preserve the high ligation of the inferior mesenteric artery during the rectal surgery.
干预措施: not preserving the left colic artery (Procedure)
结局指标
主要结局
The Blood Pressure of the Arterial Arcade
时间窗: after ligating the inferior mesentric artery or superior rectal artery
次要结局
- Distal Colon Length(after digestive tract reconstruction)
研究者
Jian Suo
Headmaster, Dept.of General Surgery
The First Hospital of Jilin University