Predicting Risk Factors of Postoperative Hypocalcemia After Total Thyroidectomy: is Safe Discharge Without Supplementation Possible?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 477
- 试验地点
- 1
- 主要终点
- calcium and PTH thresholds
研究概览
简要总结
With increasing economic pressures to shorten the length of hospital stay, there has been much recent interest in studying risk factors for the development of postoperative hypocalcemia.
The aim of this study was to investigate in patients undergoing total thyroidectomy whether serum calcium and/or PTH levels can predict hypoparathyroidism.
详细描述
Our study consists of analyzing the calcium (mmol/l) and PTH (pmol/l) levels on the first postoperative day. Postoperative treatment with calcium and vitamin D and the length of hospital stay is also taken into consideration.
We also analyze post-operative complications.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Total thyroidectomy
排除标准
- •concomitant parathyroidectomy for primary hyperparathyroidism
- •lobectomy only
- •completion thyroidectomy
- •central and lateral neck dissection
- •patients with calcium and/or vitamin D supplementation prior surgery
- •patients with known and significant osteoporosis and renal failure
结局指标
主要结局
calcium and PTH thresholds
时间窗: one years
For all 477 patients postoperative calcium and PTH levels and treatment with calcium and vitamin D will be analyzed. Objective is to identify the calcium and PTH thresholds at which the patient after total thyroidectomy can be discharged without risk of hypocalcemia.
次要结局
未报告次要终点
研究者
Paladino Nunzia Cinzia
Principal Investigator
Aix Marseille Université