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Predicting Risk Factors of Postoperative Hypocalcemia After Total Thyroidectomy

Completed
Conditions
Hypoparathyroidism
Interventions
Other: analysis of hypocalcemia
Registration Number
NCT04372225
Lead Sponsor
Aix Marseille Université
Brief Summary

With increasing economic pressures to shorten the length of hospital stay, there has been much recent interest in studying risk factors for the development of postoperative hypocalcemia.

The aim of this study was to investigate in patients undergoing total thyroidectomy whether serum calcium and/or PTH levels can predict hypoparathyroidism.

Detailed Description

Our study consists of analyzing the calcium (mmol/l) and PTH (pmol/l) levels on the first postoperative day. Postoperative treatment with calcium and vitamin D and the length of hospital stay is also taken into consideration.

We also analyze post-operative complications.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
477
Inclusion Criteria

• Total thyroidectomy

Exclusion Criteria
  • concomitant parathyroidectomy for primary hyperparathyroidism
  • lobectomy only
  • completion thyroidectomy
  • central and lateral neck dissection
  • patients with calcium and/or vitamin D supplementation prior surgery
  • patients with known and significant osteoporosis and renal failure

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
477 patientsanalysis of hypocalcemiathe biological tests of 477 patients undergoing total thyroidectomy were analyzed
Primary Outcome Measures
NameTimeMethod
calcium and PTH thresholdsone years

For all 477 patients postoperative calcium and PTH levels and treatment with calcium and vitamin D will be analyzed.

Objective is to identify the calcium and PTH thresholds at which the patient after total thyroidectomy can be discharged without risk of hypocalcemia.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Conception Hospital

🇫🇷

Marseille, France

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