Comparing two ways of using dexamethasone to reduce sore throat after surgery

Phase 4

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2025/05/087989
• Lead Sponsor: Department of Anaesthesia and Pain Medicine Pt.JNM Medical College Raipur

Brief Summary

This is the randomized interventional study comparing nebulized dexamethasone vs intracuff dexamethasone for prevention of sore throat.

Patients requiring endotracheal intubation will enrolled with sample size of 60 (30 in each group).

Primary outcome will be the incidence of sore throat with nebulized vs intracuff dexamethasone.

secondary outcome will be severity of post operative sore throat, incidence and severity of post op hoarseness and incidence and severity of post op cough with nebulized vs intracuff dexamethasone.

Assessment will be done on 2hr,6hr,12hr and 24hr in post op period.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-03-06
• Last Update Posted: 2025-05-23

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

ASA grade 1 and 2 MPG grade 1 and 2 Surgery in supine position under general anaesthesia requiring endotracheal intubation.

Exclusion Criteria

Patient refusal Pregnancy Known allergy with study drug Preexisting laryngeal and pharyngeal disease Patients requiring orogastric tube insertion Patient undergoing oropharyngeal surgery Patients on steroids or NSAIDs Patients with severe GERD Patients having sore throat.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To study the incidence of post operative sore throat with intracuff vs nebulized dexamethasone	At 2hr,6hr, 12hr and 24hr

Secondary Outcome Measures

Name	Time	Method
To compare the severity of POST with intracuff vs nebulized dexamethasone	To compare the incidence & severity of post op hoareseness with intracuff vs nebulized dexamethasone

Trial Locations

Locations (1)

Dr. Bhim Rao Ambedkar Memorial Hospital; 🇮🇳 Raipur, CHHATTISGARH, India

Dr. Bhim Rao Ambedkar Memorial Hospital

🇮🇳Raipur, CHHATTISGARH, India

Dr Shalu kushwaha

Principal investigator

7440935927

shalukushwaha505@gmail.com