EUCTR2004-002366-38-DE进行中（未招募）不适用
Fluoride uptake and remineralisation of incipient carious lesions following the application of fluoride fluids with different fluoride concentrations -
GABA GmbH0 个研究点开始时间: 2004年10月4日最近更新:
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Written declaration of informed consent
- •Age 18-60 years
- •At least 20 teeth
- •Good general health, as assessed by investigator
- •Healthy or prosthetically, restored and periodontally-sound dentition
- •Average oral hygiene (cleaning the teeth at least twice a day)
- •Agreement of test subjects not to use any oral hygiene products other than the test products and toothpaste provided for the duration of the study; the use of non-fluoridated oral hygiene agents is allowed
- •Flow rate of stimulated saliva = 0.7 ml/min
- •Moderate to high buffer capacity of saliva
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Ongoing oral or dental treatment except for emergency treatment
- •Known allergic reaction to an oral hygiene product and/or medication and/or dental material previously used in the mouth or pharynx
- •Existing allergy to one of teh components of the test products or the standard toothpaste
- •Unphysiological mobility of the teeth
- •Pathological changes of the oral mucusa, eg. acute ulcerating gingivitis, acute herpetic gingivostomatitis, recurrent aphthous ulceration or systemic illnesses with oral manifestations
- •Use of fluoride-containing products (Pastes, mouthrinses) within 14 days prior to the introduction of the intra-oral appliances
- •Use of fluoride-containing products: gels, tablets, varnishes, fillings etc., or of erosive bronchiolytics or anti-asthmatics within 30 days prior to the introduction of the intra-oral specimen holder
- •Pregnancy or breast feeding
- •Participation in another clinical trial either currently or within the last 30 days
- •Antibiotic therapy within the past 3 months
- •Any non-permitted therapy
- •Eating disorders (e.g.bulimia, anorexia nervosa)
研究者
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