The Body and Brain in Irritable Bowel Syndrome (IBS) Study: Evaluating the effects of fructans on gastrointestinal symptoms in adults with mild to moderate IBS

Not Applicable

• Conditions: Irritable bowel syndrome; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12624001042538
• Lead Sponsor: Deakin University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-08-28
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Australian residents willing to drive to Geelong for one study visit
• Aged 18-65 years
• IBS diagnosed by GP or gastroenterologist and meeting the Rome IV criteria (screened at
baseline)
• Mild or moderate IBS symptoms (IBS-SSS score 75-300 pts)
• Familiar with fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) and fructans
• Access to internet on phone, tablet or computer
• Able to read and understand materials written in English

Exclusion Criteria

• Patient-reported diagnosis of other gastrointestinal diseases (e.g. inflammatory bowel disease, acute diverticulitis coeliac disease)
• Patient-reported diagnosis of unstable mental illness (e.g. unstable schizophrenia, other psychotic disorders)
• Patient-reported diagnosis of current major medical conditions (e.g., cancer, dementia, type 1 and type 2 diabetes, cardiovascular disease, heart failure, chronic obstructive pulmonary disease).
• Patient-reported alcohol/substance abuse
• Eating disorder such as anorexia nervosa and bulimia nervosa (i.e. patient-reported or score equal to or greater than 3 on the ‘Sick, Control, One, Fat, Food’ (SCOFF) questionnaire)
• Pregnant, planning pregnancy or lactating
• Previous extensive GI surgery or stenotic disease e.g., major bowel resection, cholecystectomy (not appendicectomy or haemorrhoidectomy)
• Commenced prebiotics, probiotics or antibiotics in the past 4 weeks
• Current participation in another clinical trial
• Commencement or change in therapy for irritable bowel syndrome in the past month.

Study & Design

• Study Type: Interventional
• Study Design: Not specified