Milrinone in status asthmaticus

Not Applicable

Completed

• Conditions: Respiratory; bronchial asthma

• Registration Number: PACTR201802002998973
• Lead Sponsor: dramrsobhy

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-21
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

patients ranging age 18-50 years old arriving at the emergency room with life-threatening asthma according to the criteria of the British Guideline on the management of asthma 2008, revised October 2014. Life-threatening asthma is defined as any one or more of the following criteria:
¿PEF <33% best or predicted
¿SpO2 <92%
¿PaO2 <8 kPa (60 mm Hg)
¿Normal PaCO2 (4.6-6.0 kPa) (35-45 mm Hg)
¿Silent chest
¿Cyanosis
¿Poor respiratory effort
¿Arrhythmia
¿Exhaustion, altered conscious level
¿Hypotension

Exclusion Criteria

¿patientes with pre-existing heart failure, hypotensive patients, stenotic or obstructive valvular disease or other outlet obstruction, and patients with pre-existing arrhythmia

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
assess the effectiveness of using milrinone as a rescue drug in life-threatening bronchial asthma

Secondary Outcome Measures

Name	Time	Method
reducing the number of patients requiring mechanical ventilation.