NCT01067638
Completed
Phase 4
The Effect of Tranexamic Acid on Postoperative Blood Loss and Coagulation in Patients With Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft; Double Blind Randomized Control Study
Overview
- Phase
- Phase 4
- Intervention
- Tranexamic Acid
- Conditions
- Coronary Artery Occlusive Disease
- Sponsor
- Yonsei University
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- Tranexamic acid significantly reduce the amount and incidence of homologous transfusion in anemic patients undergoing off-pump coronary artery bypass (OPCAB)
- Status
- Completed
- Last Updated
- 15 years ago
Overview
Brief Summary
The Effect of Tranexamic Acid on Postoperative Blood loss and Coagulation in Patients with Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft; double blind randomized control study.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Fifty patients undergoing OPCAB with preoperative hematocrit levels lower than 35%
Exclusion Criteria
- •Patient who has
- •Open heart surgery history before
- •Thrombosis history
- •Myocardial infarction (MI) within 7days recently
- •Liver or Kidney disease
- •been scheduled emergency surgery
Arms & Interventions
tranexamic acid
Tranexamic Acid on Postoperative Blood loss and Coagulation in Patients with Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft
Intervention: Tranexamic Acid
Outcomes
Primary Outcomes
Tranexamic acid significantly reduce the amount and incidence of homologous transfusion in anemic patients undergoing off-pump coronary artery bypass (OPCAB)
Time Frame: Check the amount 3 times before sugery and 24 hours after surgery
Study Sites (1)
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