ISRCTN63852508
Completed
未知
A prospective, randomized, parallel group, single blinded, controlled, multi-center, non-paired superiority trial to compare the effect of short-term 'in house' oxygenated hypothermic machine perfusion preservation after static cold storage to static cold storage alone in transplantation of expanded criteria donor (ECD) kidneys donated after brain death
niversity of Oxford (UK)0 sites262 target enrollmentApril 9, 2014
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- niversity of Oxford (UK)
- Enrollment
- 262
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
2021 results in https://pubmed.ncbi.nlm.nih.gov/33881456/ (added 22/04/2021)
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Kidneys from brain dead donors fulfilling the United Network for Organ Sharing ECD criteria
- •1\. At least 18 years old.
- •2\. Listed for renal transplantation due to end stage renal disease within one of the participating centers
- •3\. The transplantation is the participant's first or re\-transplantation
Exclusion Criteria
- •1\. Kidney used for a multi\-organ transplantation
- •2\. Donor aged 85 or older
- •3\. Donation after cardiac death
- •4\. Kidney used for double\-kidney transplantation within the same recipient
- •1\. Simultaneous participation in another perfusion trial
- •2\. Scheduled to undergo multi\-organ transplantation
- •3\. Planned dual\-kidney transplantation
- •4\. Both kidneys being transplanted within the same recipient
- •5\. Is unable or unwilling to provide informed consent
Outcomes
Primary Outcomes
Not specified
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