COPE-POMP: 'in house' pre-implantation oxygenated hypothermic machine perfusion reconditioning after cold storage versus cold storage alone in expanded criteria donor (ECD) kidneys from brain dead donors

Not Applicable

Completed

• Conditions: Machine perfusion preservation techniques for ECD kidneys; Surgery

• Registration Number: ISRCTN63852508
• Lead Sponsor: niversity of Oxford (UK)

Brief Summary

2021 results in https://pubmed.ncbi.nlm.nih.gov/33881456/ (added 22/04/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-04-09
• Study Completion: 2019-07-01
• Last Update Posted: 3 May 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 262

Inclusion Criteria

Donors:
1. Kidneys from brain dead donors fulfilling the United Network for Organ Sharing ECD criteria

Recipient:
1. At least 18 years old.
2. Listed for renal transplantation due to end stage renal disease within one of the participating centers
3. The transplantation is the participant's first or re-transplantation

Exclusion Criteria

Donor:
1. Kidney used for a multi-organ transplantation
2. Donor aged 85 or older
3. Donation after cardiac death
4. Kidney used for double-kidney transplantation within the same recipient

Recipient:
1. Simultaneous participation in another perfusion trial
2. Scheduled to undergo multi-organ transplantation
3. Planned dual-kidney transplantation
4. Both kidneys being transplanted within the same recipient
5. Is unable or unwilling to provide informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified