Magnetic Resonance Cholangiopancreatography in Living Liver Donors and its relationship with post operative Recipient biliary complications - Open Label Randomised Controlled Trial
试验速览
- 阶段
- 1/2 期
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To Compare early biliary complications in Liver transplant recipient within first 6 months (Bile Leak, Biliary anastomotic stricture)
研究概览
简要总结
Living donor liver transplantation is widely accepted as an life-saving treatment for patients with end-stage liver diseases. Careful donor selection is essential to maximize the success and minimize the risk of postoperative complications in donors and recipients. Mapping of biliary anatomy is one of the critical assessments for donor selection and surgical planning ,Biliary reconstruction is considered as the “Achilles heel” of liver transplantation and adequate imaging assessment of biliary anatomy can largely benefit the biliary anastomosis. Preoperative imaging assessment of biliary anatomy is good for the selection of donors but may not indispensable for surgical planning and Intraoperative confirmative assessment of biliary anatomy with IOC was essential
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •All prospective voluntary healthy liver donor of age 18-55.
排除标准
- •1.Type C/D Portal vein anatomy 2.Left sided Gallbladder 3.Right Posterior Graft 4.Recipients undergoing Hepaticojejunostomy.
结局指标
主要结局
To Compare early biliary complications in Liver transplant recipient within first 6 months (Bile Leak, Biliary anastomotic stricture)
时间窗: 3 months, 6 months
次要结局
- Prevalence of biliary duct variations(1 month)
- Donor biliary complications in both group
- Identify Risk factors for early Biliary complications in recipients
- Change of operative plan- Left vs Right Lobe
研究者
Atul Renjit
Institute of Liver and Biliary Sciences