Comparison Between Effect of Vitamin D Versus Dexmedetomidine in Patients With Head Trauma Using Interleukin 6
Completed
- Conditions
- Traumatic Brain Injury
- Registration Number
- NCT06565338
- Lead Sponsor
- Minia University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Inclusion Criteria:<br><br> - Both Gender.<br><br> - Age (18-50)<br><br> - GCS (8-12)<br><br> - Pt with traumatic brain insult who not indicated surgical intervention<br><br>Exclusion Criteria:<br><br> - Prior severe disability.<br><br> - Isolated brain system lesions.<br><br> - History of underlying neurologic, metabolic or psychiatric disorders.<br><br> - Alcohol or drug abuse.<br><br> - Pregnancy.<br><br> - Patients with intracranial hemorrhage who indicated surgical evacuation.<br><br> - Multisystem life-threatening trauma.<br><br> - GCS > 12 & <8.<br><br> - Vitamin d deficiency.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Observational [Patient Registry]
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint aims to measure the inflammatory markers level (interleukin 6'CRP'ESR).
- Secondary Outcome Measures
Name Time Method The secondary endpoints aim to compare ICU stay, disability ,morbidity and mortality in both groups