Prophylactic infusion of CD4 positive donor lymphocytes early after T-cell depleted stem cell transplantatio
Completed
- Conditions
- Haematological malignancyCancerLeukaemia of unspecified cell type
- Registration Number
- ISRCTN51398568
- Lead Sponsor
- eiden University Medical Centre (Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1. Both males and females
2. Age from 18 to 70 years
3. Patients with acute myeloid leukaemia (AML), myelodysplasia (MDS), acute lymphocytic leukaemia (ALL), chronic myeloid leukaemia (CML) in accelerated phase or blastic transformation, chronic lymphocytic leukaemia (CLL), multiple myeloma (MM) or aggressive lymphoma, who received an allogeneic stem cell transplantation.
Exclusion Criteria
1. Systemic immunosuppressive treatment
2. Progressive Graft Versus Host Disease (GVHD)
3. GVHD of the skin greater than grade 2
4. Progressive disease needing cytoreductive treatment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method