Kochujang Decreases Visceral Fat and Improves Lipids Profiles
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 60
- 主要终点
- Visceral fat
研究概览
简要总结
With the epidemic of obesity and diabetes growing around the world, Kochujang (KCJ) may be potentially effective in preventing and treating obesity and cardiovascular risks if proven in humans. However, human trial still have not been reported with KCJ supplementation. In the present study, we investigated the hypothesis that KCJ supplementation can be decrease the body fat and improve blood lipid profiles in overweight adults.
详细描述
The aim of this study was to evaluate the efficacy of KCJ supplementation on anthropometric parameters, visceral fat/subcutaneous fat, and blood lipid profiles in overweight subjects.
Sixty overweight subjects with BMI >25 kg/m2 and waist-hip-ratio (WHR) ≥ 0.90 for men and ≥ 0.85 for women were randomly assigned to either KCJ supplement (n=30, 32 g/day) or placebo (n=30, 32 g/day) group for 12 weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 19 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI >25kg/m2 and 2)Waist-Hip Ratio (WHR): WHR> 0.90(male), WHR>0.85(female)
排除标准
- •lipid metabolic disorders
- •>10% changes in body weight in the past 3 months
- •Cardiovascular disease such as arrhythmia, heart failure, myocardial infarction, and wearing pacemaker
- •Allergy or hypersensitivity to any of the ingredients in the test products - History of reaction to any of the experimental products or of gastrointestinal diseases such as Crohn's disease or gastrointestinal surgery
- •Participation in other clinical trials within the past 2 months
- •Abnormal hepatic liver function, renal disease such as acute
- •chronic renal failure, nephrotic syndrome
- •Use of anti-psychosis drug therapy within 2 months
- •Laboratory test, medical or psychological conditions deemed by the investigators to interfere with successful participation in the study
- •History of alcohol or substance abuse
- •Pregnancy or breastfeeding
结局指标
主要结局
Visceral fat
时间窗: after 12 weeks of consumption
次要结局
- Body Mass Index(after 12 weeks of consumption)
- Subcutaneous fat(after 12weeks)
- Triglyceride(after 12week of consumption)
- Atherosclerosis index(after 12weeks of consumption)
- Apolipoprotein(after 12weeks of consumption)